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Interactions of Methylene Blue with Human Disulfide Reductases and Their Orthologues from Plasmodium falciparum

Methylene blue (MB) has experienced a renaissance mainly as a component of drug combinations against Plasmodium falciparum malaria. Here, we report biochemically relevant pharmacological data on MB such as rate constants for the uncatalyzed reaction of MB at pH 7.4 with cellular reductants like NAD(...

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Bibliografski detalji
Glavni autori: Buchholz, Kathrin, Schirmer, R. Heiner, Eubel, Jana K., Akoachere, Monique B., Dandekar, Thomas, Becker, Katja, Gromer, Stephan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223905/
https://ncbi.nlm.nih.gov/pubmed/17967916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00773-07
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