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Interactions of Methylene Blue with Human Disulfide Reductases and Their Orthologues from Plasmodium falciparum

Methylene blue (MB) has experienced a renaissance mainly as a component of drug combinations against Plasmodium falciparum malaria. Here, we report biochemically relevant pharmacological data on MB such as rate constants for the uncatalyzed reaction of MB at pH 7.4 with cellular reductants like NAD(...

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Autors principals: Buchholz, Kathrin, Schirmer, R. Heiner, Eubel, Jana K., Akoachere, Monique B., Dandekar, Thomas, Becker, Katja, Gromer, Stephan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223905/
https://ncbi.nlm.nih.gov/pubmed/17967916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00773-07
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