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Phosphorylated tau can promote tubulin assembly

Phosphorylation can affect the function of microtubule-associated protein tau. Here, the human brain tau with 441 amino acids was phosphorylated by cyclic-AMP-dependent protein kinase (PKA) or glycogen synthase kinase-3β. PKA-phosphorylated tau (2.7 mol phosphates/mol) does not promote tubulin assem...

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Detalhes bibliográficos
Main Authors: Tseng, Huang-Chun, Lu, Quan, Henderson, Eric, Graves, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22238/
https://ncbi.nlm.nih.gov/pubmed/10449722
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