A carregar...
Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation.
The p16 (MTS1) tumour-suppressor gene is a cyclin-dependent kinase (cdk) inhibitor that decelerates the cell cycle by inactivating the cdks that phosphorylate the retinoblastoma tumour-suppressor gene (Rb) protein (pRb). In cervical cancers, pRb is inactivated by the HPV E7 oncoprotein or by mutatio...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1997
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223509/ https://ncbi.nlm.nih.gov/pubmed/9166931 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|