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Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras.

Recent investigations have shown the presence of ras gene mutations and human papillomavirus (HPV) DNA in prostate carcinomas. In the present study, secondary adult human prostatic epithelial cells, upon transfection with a plasmid containing the entire HPV-18 genome, acquired an indefinite life-spa...

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Detalhes bibliográficos
Main Authors: Rhim, J S, Webber, M M, Bello, D, Lee, M S, Arnstein, P, Chen, L S, Jay, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45338/
https://ncbi.nlm.nih.gov/pubmed/7991549
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