Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras.

Recent investigations have shown the presence of ras gene mutations and human papillomavirus (HPV) DNA in prostate carcinomas. In the present study, secondary adult human prostatic epithelial cells, upon transfection with a plasmid containing the entire HPV-18 genome, acquired an indefinite life-spa...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Rhim, J S, Webber, M M, Bello, D, Lee, M S, Arnstein, P, Chen, L S, Jay, G
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1994
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.11874
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