Double-Stranded RNA-Binding Protein Regulates Vascular Endothelial Growth Factor mRNA Stability, Translation, and Breast Cancer Angiogenesis

Vascular endothelial growth factor (VEGF) is a key angiogenic factor expressed under restricted nutrient and oxygen conditions in most solid tumors. The expression of VEGF under hypoxic conditions requires transcription through activated hypoxia-inducible factor 1 (HIF-1), increased mRNA stability,...

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Detalhes bibliográficos
Main Authors: Vumbaca, Frank, Phoenix, Kathryn N., Rodriguez-Pinto, Daniel, Han, David K., Claffey, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223436/
https://ncbi.nlm.nih.gov/pubmed/18039850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02078-06
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