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Protein Phosphatase 2A Subunit PR70 Interacts with pRb and Mediates Its Dephosphorylation

The retinoblastoma tumor suppressor protein (pRb) regulates cell proliferation and differentiation via phosphorylation-sensitive interactions with specific targets. While the role of cyclin/cyclin-dependent kinase complexes in the modulation of pRb phosphorylation has been extensively studied, relat...

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Detalhes bibliográficos
Main Authors: Magenta, Alessandra, Fasanaro, Pasquale, Romani, Sveva, Di Stefano, Valeria, Capogrossi, Maurizio C., Martelli, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223420/
https://ncbi.nlm.nih.gov/pubmed/17991896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00480-07
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