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Transcript-Specific Decapping and Regulated Stability by the Human Dcp2 Decapping Protein

mRNA decapping is a critical step in the control of mRNA stability and gene expression and is carried out by the Dcp2 decapping enzyme. Dcp2 is an RNA binding protein that must bind RNA in order to recognize the cap for hydrolysis. We demonstrate that human Dcp2 (hDcp2) preferentially binds to a sub...

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Bibliografiske detaljer
Main Authors: Li, You, Song, Man-Gen, Kiledjian, Megerditch
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223397/
https://ncbi.nlm.nih.gov/pubmed/18039849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01727-07
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