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Altered Quality Control in the Endoplasmic Reticulum Causes Cortical Dysplasia in Knock-In Mice Expressing a Mutant BiP

Binding immunoglobulin protein (BiP) is an endoplasmic reticulum (ER) molecular chaperone that is central to ER function. We examined knock-in mice expressing a mutant BiP in order to elucidate physiological processes that are sensitive to BiP functions during development and adulthood. The mutant B...

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Detalhes bibliográficos
Main Authors: Mimura, Naoya, Yuasa, Shigeki, Soma, Miho, Jin, Hisayo, Kimura, Keita, Goto, Shigemasa, Koseki, Haruhiko, Aoe, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223281/
https://ncbi.nlm.nih.gov/pubmed/17954555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00473-07
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