Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade

Influenza viruses replicate within the nucleus of infected cells. Viral genomic RNA, three polymerase subunits (PB2, PB1, and PA), and the nucleoprotein (NP) form ribonucleoprotein complexes (RNPs) that are exported from the nucleus late during the infectious cycle. The virus-induced Raf/MEK/ERK (MA...

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Bibliografiska uppgifter
Huvudupphovsmän: Marjuki, Henju, Yen, Hui-Ling, Franks, John, Webster, Robert G, Pleschka, Stephan, Hoffmann, Erich
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222635/
https://ncbi.nlm.nih.gov/pubmed/18053252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-134
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