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Suppression of lipopolysaccharide- and tumour necrosis factor-α-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation

There is accumulating evidence that the transrepressional effect of glucocorticoids in down-regulating proinflammatory gene expression might be regulated by an action on histone acetylation. To investigate this, we studied the effect of two glucocorticoids (dexamethasone and triamcinolone acetonide)...

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Autors principals: Tsaprouni, L G, Ito, K, Adcock, I M, Punchard, N
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219273/
https://ncbi.nlm.nih.gov/pubmed/17711487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03484.x
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