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Induction of interleukins IL-6 and IL-8 by siRNA

The HIV-1 co-receptor CCR5 has been thought a relevant target for small interfering RNA (siRNA)-based therapeutics. However, recent findings suggest that siRNA can stimulate innate cytokine responses in mammals. All siRNA agents tested were able to down-regulate the expression of CCR5, albeit with d...

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Detaylı Bibliyografya
Asıl Yazarlar: Pauls, E, Senserrich, J, Bofill, M, Clotet, B, Esté, J A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810454/
https://ncbi.nlm.nih.gov/pubmed/17177979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03263.x
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