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RGD-avidin–biotin pretargeting to α(v)β(3) integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand (TRAIL)

Recombinant TNF-related apoptosis-inducing ligand (TRAIL) is considered a powerful and selective inducer of tumor cell death. We hypothesize that TRAIL’s potential as anticancer agent can be enhanced further by promoting its accumulation in tumor tissue. For this purpose, we developed TRAIL complexe...

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Bibliografische gegevens
Hoofdauteurs: Tarrus, Marc, van der Sloot, Almer M., Temming, Kai, Lacombe, Marie, Opdam, Frank, Quax, Wim J., Molema, Grietje, Poelstra, Klaas, Kok, Robbert J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2007
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Original Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217618/
https://ncbi.nlm.nih.gov/pubmed/18071905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-007-0166-5
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