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Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework

BACKGROUND: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Standard analyses of SAGE data, however, ignore the fact that the probability of generating an observable tag varies across ge...

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Autori principali: Gilchrist, Michael A, Qin, Hong, Zaretzki, Russell
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217564/
https://ncbi.nlm.nih.gov/pubmed/17945026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-403
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