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Functional Roles of Nonconserved Structural Segments in CFTR's NH(2)-terminal Nucleotide Binding Domain
The cystic fibrosis transmembrane conductance regulator (CFTR), encoded by the gene mutated in cystic fibrosis patients, belongs to the family of ATP-binding cassette (ABC) proteins, but, unlike other members, functions as a chloride channel. CFTR is activated by protein kinase A (PKA)-mediated phos...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2217481/ https://ncbi.nlm.nih.gov/pubmed/15596536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409174 |
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