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Large Diameter of Palytoxin-induced Na/K Pump Channels and Modulation of Palytoxin Interaction by Na/K Pump Ligands

Palytoxin binds to Na/K pumps to generate nonselective cation channels whose pore likely comprises at least part of the pump's ion translocation pathway. We systematically analyzed palytoxin's interactions with native human Na/K pumps in outside-out patches from HEK293 cells over a broad r...

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Autors principals: Artigas, Pablo, Gadsby, David C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217460/
https://ncbi.nlm.nih.gov/pubmed/15024043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308964
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