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Na(+)/K(+)-pump ligands modulate gating of palytoxin-induced ion channels

The Na(+)/K(+) pump is a ubiquitous P-type ATPase that binds three cytoplasmic Na(+) ions deep within its core where they are temporarily occluded before being released to the extracellular surface. The 3Na(+)/2K(+)-exchange transport cycle is completed when two extracellular K(+) ions bind and beco...

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Detalhes bibliográficos
Main Authors: Artigas, Pablo, Gadsby, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141024/
https://ncbi.nlm.nih.gov/pubmed/12518045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0135849100
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