SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

Measurements of membrane capacitance were applied to dissect the cellular mechanisms underlying PKA-dependent and -independent stimulation of insulin secretion by cyclic AMP. Whereas the PKA-independent (Rp-cAMPS–insensitive) component correlated with a rapid increase in membrane capacitance of ∼80...

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Main Authors: Eliasson, Lena, Ma, Xiaosong, Renström, Erik, Barg, Sebastian, Berggren, Per-Olof, Galvanovskis, Juris, Gromada, Jesper, Jing, Xingjun, Lundquist, Ingmar, Salehi, Albert, Sewing, Sabine, Rorsman, Patrik
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217330/
https://ncbi.nlm.nih.gov/pubmed/12601083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028707
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