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Molecular Architecture of Full-Length KcsA : Role of Cytoplasmic Domains in Ion Permeation and Activation Gating

The molecular architecture of the NH(2) and COOH termini of the prokaryotic potassium channel KcsA has been determined using site-directed spin-labeling methods and paramagnetic resonance EPR spectroscopy. Cysteine mutants were generated (residues 5–24 and 121–160) and spin labeled, and the X-band C...

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Autors principals: Cortes, D. Marien, Cuello, Luis G., Perozo, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217246/
https://ncbi.nlm.nih.gov/pubmed/11158168
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