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Locating the Anion-selectivity Filter of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel

The cystic fibrosis transmembrane conductance regulator forms an anion-selective channel; the site and mechanism of charge selectivity is unknown. We previously reported that cysteines substituted, one at a time, for Ile331, Leu333, Arg334, Lys335, Phe337, Ser341, Ile344, Arg347, Thr351, Arg352, and...

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Detalles Bibliográficos
Main Authors: Cheung, Min, Akabas, Myles H.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217075/
https://ncbi.nlm.nih.gov/pubmed/9089437
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