O(2) sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase

The rapid response to hypoxia in the pulmonary artery (PA), carotid body, and ductus arteriosus is partially mediated by O(2)-responsive K(+) channels. K(+) channels in PA smooth muscle cells (SMCs) are inhibited by hypoxia, causing membrane depolarization, increased cytosolic calcium, and hypoxic p...

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Autores principales: Archer, Stephen L., Reeve, Helen L., Michelakis, Evangelos, Puttagunta, Lakshmi, Waite, Ross, Nelson, Daniel P., Dinauer, Mary C., Weir, E. Kenneth
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22167/
https://ncbi.nlm.nih.gov/pubmed/10393927
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