O(2) sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase

The rapid response to hypoxia in the pulmonary artery (PA), carotid body, and ductus arteriosus is partially mediated by O(2)-responsive K(+) channels. K(+) channels in PA smooth muscle cells (SMCs) are inhibited by hypoxia, causing membrane depolarization, increased cytosolic calcium, and hypoxic p...

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Autors principals: Archer, Stephen L., Reeve, Helen L., Michelakis, Evangelos, Puttagunta, Lakshmi, Waite, Ross, Nelson, Daniel P., Dinauer, Mary C., Weir, E. Kenneth
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22167/
https://ncbi.nlm.nih.gov/pubmed/10393927
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