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Rotenone Activates Phagocyte NADPH Oxidase through Binding to Its Membrane Subunit gp91(phox)

Rotenone, a widely used pesticide, reproduces Parkinsonism in rodents and associates with increased risk for Parkinson’s disease. We previously reported rotenone increased superoxide production through stimulating microglial phagocyte NADPH oxidase (PHOX). The present study identified a novel mechan...

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Detalhes bibliográficos
Main Authors: Zhou, Hui, Zhang, Feng, Chen, Shih-heng, Zhang, Dan, Wilson, Belinda, Hong, Jau-shyong, Gao, Hui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253173/
https://ncbi.nlm.nih.gov/pubmed/22094225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.488
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