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Rotenone Activates Phagocyte NADPH Oxidase through Binding to Its Membrane Subunit gp91(phox)

Rotenone, a widely used pesticide, reproduces Parkinsonism in rodents and associates with increased risk for Parkinson’s disease. We previously reported rotenone increased superoxide production through stimulating microglial phagocyte NADPH oxidase (PHOX). The present study identified a novel mechan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Hui, Zhang, Feng, Chen, Shih-heng, Zhang, Dan, Wilson, Belinda, Hong, Jau-shyong, Gao, Hui-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253173/
https://ncbi.nlm.nih.gov/pubmed/22094225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.488
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