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Rotenone Activates Phagocyte NADPH Oxidase through Binding to Its Membrane Subunit gp91(phox)

Rotenone, a widely used pesticide, reproduces Parkinsonism in rodents and associates with increased risk for Parkinson’s disease. We previously reported rotenone increased superoxide production through stimulating microglial phagocyte NADPH oxidase (PHOX). The present study identified a novel mechan...

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Hlavní autoři: Zhou, Hui, Zhang, Feng, Chen, Shih-heng, Zhang, Dan, Wilson, Belinda, Hong, Jau-shyong, Gao, Hui-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253173/
https://ncbi.nlm.nih.gov/pubmed/22094225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.488
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