Rotenone Activates Phagocyte NADPH Oxidase through Binding to Its Membrane Subunit gp91(phox)

Rotenone, a widely used pesticide, reproduces Parkinsonism in rodents and associates with increased risk for Parkinson’s disease. We previously reported rotenone increased superoxide production through stimulating microglial phagocyte NADPH oxidase (PHOX). The present study identified a novel mechan...

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Bibliographic Details
Main Authors: Zhou, Hui, Zhang, Feng, Chen, Shih-heng, Zhang, Dan, Wilson, Belinda, Hong, Jau-shyong, Gao, Hui-Ming
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253173/
https://ncbi.nlm.nih.gov/pubmed/22094225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.488
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