Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5

The proliferation and differentiation of hematopoietic stem cells (HSCs) is finely regulated by extrinsic and intrinsic factors via various signaling pathways. Here we have shown that, similar to mice deficient in the lipid phosphatase SHIP, loss of 2 Src family kinases, Lyn and Hck, profoundly affe...

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Main Authors: Xiao, Wenbin, Hong, Hong, Kawakami, Yuko, Lowell, Clifford A., Kawakami, Toshiaki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214849/
https://ncbi.nlm.nih.gov/pubmed/18246197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34013
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