Carregant...

Inhibitory Phosphorylation of Separase Is Essential for Genome Stability and Viability of Murine Embryonic Germ Cells

Activity of separase, a cysteine protease that cleaves sister chromatid cohesin at the onset of anaphase, is tightly regulated to ensure faithful chromosome segregation and genome stability. Two mechanisms negatively regulate separase: inhibition by securin and phosphorylation on serine 1121. To gau...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Huang, Xingxu, Andreu-Vieyra, Claudia V, York, J. Philippe, Hatcher, Rashieda, Lu, Tao, Matzuk, Martin M, Zhang, Pumin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214812/
https://ncbi.nlm.nih.gov/pubmed/18232736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060015
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!