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Securin and Separase Phosphorylation Act Redundantly to Maintain Sister Chromatid Cohesion in Mammalian Cells

The spindle assembly checkpoint monitors the integrity of the spindle microtubules, which attach to sister chromatids at kinetochores and play a vital role in preserving genome stability by preventing missegregation. A key target of the spindle assembly checkpoint is securin, the separase inhibitor....

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書目詳細資料
Main Authors: Huang, Xingxu, Hatcher, Rashieda, York, J. Philippe, Zhang, Pumin
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237078/
https://ncbi.nlm.nih.gov/pubmed/16030258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0190
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