Securin and Separase Phosphorylation Act Redundantly to Maintain Sister Chromatid Cohesion in Mammalian Cells

The spindle assembly checkpoint monitors the integrity of the spindle microtubules, which attach to sister chromatids at kinetochores and play a vital role in preserving genome stability by preventing missegregation. A key target of the spindle assembly checkpoint is securin, the separase inhibitor....

Full description

Saved in:
Bibliographic Details
Main Authors: Huang, Xingxu, Hatcher, Rashieda, York, J. Philippe, Zhang, Pumin
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2005
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237078/
https://ncbi.nlm.nih.gov/pubmed/16030258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0190
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items