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Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation
The ability of peroxynitrite to modify amino acid residues in glutamine synthetase (GS) and BSA is greatly influenced by pH and CO(2)(.) At physiological concentrations of CO(2) (1.3 mM), the generation of carbonyl groups (0.2–0.4 equivalents/subunit) is little affected by pH over the range of 7.2–9...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22143/ https://ncbi.nlm.nih.gov/pubmed/10393903 |
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