PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

Integrin binding to matrix proteins such as fibronectin (FN) leads to formation of focal adhesion (FA) cellular contact sites that regulate migration. RhoA GTPases facilitate FA formation, yet FA-associated RhoA-specific guanine nucleotide exchange factors (GEFs) remain unknown. Here, we show that p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lim, Yangmi, Lim, Ssang-Taek, Tomar, Alok, Gardel, Margaret, Bernard-Trifilo, Joie A., Chen, Xiao Lei, Uryu, Sean A., Canete-Soler, Rafaela, Zhai, Jinbin, Lin, Hong, Schlaepfer, William W., Nalbant, Perihan, Bokoch, Gary, Ilic, Dusko, Waterman-Storer, Clare, Schlaepfer, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213606/
https://ncbi.nlm.nih.gov/pubmed/18195107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708194
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados