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Loss of ATRX leads to chromosome cohesion and congression defects

αThalassemia/mental retardation X linked (ATRX) is a switch/sucrose nonfermenting-type ATPase localized at pericentromeric heterochromatin in mouse and human cells. Human ATRX mutations give rise to mental retardation syndromes characterized by developmental delay, facial dysmorphisms, cognitive def...

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Bibliografiske detaljer
Main Authors: Ritchie, Kieran, Seah, Claudia, Moulin, Jana, Isaac, Christian, Dick, Frederick, Bérubé, Nathalie G.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213576/
https://ncbi.nlm.nih.gov/pubmed/18227278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706083
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