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ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain

Mutations in the alpha-thalassemia mental retardation X-linked (ATRX) gene cause a spectrum of abnormalities including intellectual disability, developmental delay, seizures, and microcephaly. The ATRX protein is highly enriched at heterochromatic repetitive sequences adjacent to the centromere, and...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Ritchie, Kieran, Watson, L. Ashley, Davidson, Benjamin, Jiang, Yan, Bérubé, Nathalie G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265753/
https://ncbi.nlm.nih.gov/pubmed/25395668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148730
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