Effects of in Vivo Cd8(+) T Cell Depletion on Virus Replication in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

The role of CD8(+) T lymphocytes in controlling replication of live, attenuated simian immunodeficiency virus (SIV) was investigated as part of a vaccine study to examine the correlates of protection in the SIV/rhesus macaque model. Rhesus macaques immunized for >2 yr with nef-deleted SIV (SIVmac...

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Main Authors: Metzner, Karin J., Jin, Xia, Lee, Fred V., Gettie, Agegnehu, Bauer, Daniel E., Di Mascio, Michele, Perelson, Alan S., Marx, Preston A., Ho, David D., Kostrikis, Leondios G., Connor, Ruth I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213531/
https://ncbi.nlm.nih.gov/pubmed/10839807
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