Dramatic Rise in Plasma Viremia after CD8(+) T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

To determine the role of CD8(+) T cells in controlling simian immunodeficiency virus (SIV) replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 monoclonal antibody, OKT8F. There was on average a 99.9% reduction of CD8 cells in peripheral blood in six infect...

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Bibliografiska uppgifter
Huvudupphovsmän: Jin, Xia, Bauer, Daniel E., Tuttleton, Sarah E., Lewin, Sharon, Gettie, Agegnehu, Blanchard, James, Irwin, Craig E., Safrit, Jeffrey T., Mittler, John, Weinberger, Leor, Kostrikis, Leondios G., Zhang, Linqi, Perelson, Alan S., Ho, David D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1999
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193038/
https://ncbi.nlm.nih.gov/pubmed/10075982
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