Temporal Analyses of Virus Replication, Immune Responses, and Efficacy in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

Despite evidence that live, attenuated simian immunodeficiency virus (SIV) vaccines can elicit potent protection against pathogenic SIV infection, detailed information on the replication kinetics of attenuated SIV in vivo is lacking. In this study, we measured SIV RNA in the plasma of 16 adult rhesu...

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Bibliographic Details
Main Authors: Connor, Ruth I., Montefiori, David C., Binley, James M., Moore, John P., Bonhoeffer, Sebastian, Gettie, Agegnehu, Fenamore, Elizabeth A., Sheridan, Kristine E., Ho, David D., Dailey, Peter J., Marx, Preston A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109989/
https://ncbi.nlm.nih.gov/pubmed/9696847
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