Essential Role of Lung Plasmacytoid Dendritic Cells in Preventing Asthmatic Reactions to Harmless Inhaled Antigen

Tolerance is the usual outcome of inhalation of harmless antigen, yet T helper (Th) type 2 cell sensitization to inhaled allergens induced by dendritic cells (DCs) is common in atopic asthma. Here, we show that both myeloid (m) and plasmacytoid (p) DCs take up inhaled antigen in the lung and present...

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Auteurs principaux: de Heer, Hendrik Jan, Hammad, Hamida, Soullié, Thomas, Hijdra, Daniëlle, Vos, Nanda, Willart, Monique A.M., Hoogsteden, Henk C., Lambrecht, Bart N.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2004
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213319/
https://ncbi.nlm.nih.gov/pubmed/15238608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040035
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