The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

The Scurfy mutation of the FoxP3 gene (FoxP3 (sf)) in the mouse and analogous mutations in human result in lethal autoimmunity. The mutation of FoxP3 in the hematopoietic cells impairs the development of regulatory T cells. In addition, development of the Scurfy disease also may require mutation of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chang, Xing, Gao, Jian Xin, Jiang, Qi, Wen, Jing, Seifers, Nick, Su, Lishan, Godfrey, Virginia L., Zuo, Tao, Zheng, Pan, Liu, Yang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2005
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213221/
https://ncbi.nlm.nih.gov/pubmed/16230479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050157
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak