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Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4(+)CD25(+) regulatory T cell proliferation
The mechanisms through which regulatory T cells accumulate in lymphoid organs of tumor-bearing hosts remain elusive. Our experiments indicate that the accumulation of CD4(+)CD25(+) regulatory T cells (T reg cells) expressing FoxP3 and exhibiting immunosuppressive function originates from the prolife...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213166/ https://ncbi.nlm.nih.gov/pubmed/16186184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050463 |
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