CD4(+)CD25(+) Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer

Tumors that progress do so via their ability to escape the antitumor immune response through several mechanisms, including developing ways to induce the differentiation and/or recruitment of CD4(+)CD25(+) Tregs. The Tregs, in turn, inhibit the cytotoxic function of T cells and NK cells, but whether...

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Détails bibliographiques
Auteurs principaux: Roux, Stephan, Apetoh, Lionel, Chalmin, Fanny, Ladoire, Sylvain, Mignot, Grégoire, Puig, Pierre-Emmanuel, Lauvau, Gregoire, Zitvogel, Laurence, Martin, François, Chauffert, Bruno, Yagita, Hideo, Solary, Eric, Ghiringhelli, François
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556241/
https://ncbi.nlm.nih.gov/pubmed/18830416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35890
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