CD4(+)CD25(+) Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer

Tumors that progress do so via their ability to escape the antitumor immune response through several mechanisms, including developing ways to induce the differentiation and/or recruitment of CD4(+)CD25(+) Tregs. The Tregs, in turn, inhibit the cytotoxic function of T cells and NK cells, but whether...

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Detalhes bibliográficos
Main Authors: Roux, Stephan, Apetoh, Lionel, Chalmin, Fanny, Ladoire, Sylvain, Mignot, Grégoire, Puig, Pierre-Emmanuel, Lauvau, Gregoire, Zitvogel, Laurence, Martin, François, Chauffert, Bruno, Yagita, Hideo, Solary, Eric, Ghiringhelli, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556241/
https://ncbi.nlm.nih.gov/pubmed/18830416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35890
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