Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence

Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses. Here, we define the function of the vaccinia virus (VV) protein A46R and show it inhibits intracellular s...

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Detalhes bibliográficos
Main Authors: Stack, Julianne, Haga, Ismar R., Schröder, Martina, Bartlett, Nathan W., Maloney, Geraldine, Reading, Patrick C., Fitzgerald, Katherine A., Smith, Geoffrey L., Bowie, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213104/
https://ncbi.nlm.nih.gov/pubmed/15767367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041442
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