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The Poxvirus Protein A52R Targets Toll-like Receptor Signaling Complexes to Suppress Host Defense

Toll-like receptors (TLRs) are crucial in the innate immune response to pathogens, in that they recognize and respond to pathogen associated molecular patterns, which leads to activation of intracellular signaling pathways and altered gene expression. Vaccinia virus (VV), the poxvirus used to vaccin...

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Detalhes bibliográficos
Main Authors: Harte, Mary T., Haga, Ismar R., Maloney, Geraldine, Gray, Pearl, Reading, Patrick C., Bartlett, Nathan W., Smith, Geoffrey L., Bowie, Andrew, O'Neill, Luke A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193841/
https://ncbi.nlm.nih.gov/pubmed/12566418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021652
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