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Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

Anthrax is an infection caused by pathogenic strains of Bacillus anthracis, which secretes a three-component toxic complex consisting of protective antigen (PA), edema factor (EF), and lethal factor (LF). PA forms binary complexes with either LF or EF and mediates their entry into host cells. Althou...

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Detalhes bibliográficos
Main Authors: Paccani, Silvia Rossi, Tonello, Fiorella, Ghittoni, Raffaella, Natale, Mariarita, Muraro, Lucia, D'Elios, Mario Milco, Tang, Wei-Jen, Montecucco, Cesare, Baldari, Cosima T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213032/
https://ncbi.nlm.nih.gov/pubmed/15699068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041557
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