Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

Golden color imparted by carotenoid pigments is the eponymous feature of the human pathogen Staphylococcus aureus. Here we demonstrate a role of this hallmark phenotype in virulence. Compared with the wild-type (WT) bacterium, a S. aureus mutant with disrupted carotenoid biosynthesis is more suscept...

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Detalhes bibliográficos
Main Authors: Liu, George Y., Essex, Anthony, Buchanan, John T., Datta, Vivekanand, Hoffman, Hal M., Bastian, John F., Fierer, Joshua, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213009/
https://ncbi.nlm.nih.gov/pubmed/16009720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050846
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