Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

Golden color imparted by carotenoid pigments is the eponymous feature of the human pathogen Staphylococcus aureus. Here we demonstrate a role of this hallmark phenotype in virulence. Compared with the wild-type (WT) bacterium, a S. aureus mutant with disrupted carotenoid biosynthesis is more suscept...

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Autors principals: Liu, George Y., Essex, Anthony, Buchanan, John T., Datta, Vivekanand, Hoffman, Hal M., Bastian, John F., Fierer, Joshua, Nizet, Victor
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213009/
https://ncbi.nlm.nih.gov/pubmed/16009720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050846
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