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Selective accumulation of differentiated CD8(+) T cells specific for respiratory viruses in the human lung

The lungs are frequently challenged by viruses, and resident CD8(+) T cells likely contribute to the surveillance of these pathogens. To obtain insight into local T cell immunity to respiratory viruses in humans, we determined the specificity, phenotype, and function of lung-residing CD8(+) T cells...

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Detalhes bibliográficos
Main Authors: de Bree, Godelieve J., van Leeuwen, Ester M.M., Out, Theo A., Jansen, Henk M., Jonkers, René E., van Lier, René A.W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212987/
https://ncbi.nlm.nih.gov/pubmed/16301748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051365
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