CD8(+) T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung

The human lung T cell compartment contains many CD8(+) T cells specific for respiratory viruses, suggesting that the lung is protected from recurring respiratory infections by a resident T cell pool. The entry site for respiratory viruses is the epithelium, in which a subset of lung CD8(+) T cells e...

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Main Authors: Piet, Berber, de Bree, Godelieve J., Smids-Dierdorp, Barbara S., van der Loos, Chris M., Remmerswaal, Ester B.M., von der Thüsen, Jan H., van Haarst, Jan M.W., Eerenberg, Jan P., ten Brinke, Anja, van der Bij, Wim, Timens, Wim, van Lier, René A.W., Jonkers, René E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104744/
https://ncbi.nlm.nih.gov/pubmed/21537083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44675
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