Continuous control of autoimmune disease by antigen-dependent polyclonal CD4(+)CD25(+) regulatory T cells in the regional lymph node

This study investigated the unresolved issue of antigen-dependency and antigen-specificity of autoimmune disease suppression by CD4(+)CD25(+) T cells (T regs). Based on autoimmune ovarian disease (AOD) in day 3 thymectomized (d3tx) mice and polyclonal T regs expressing the Thy1.1 marker, we determin...

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Bibliographic Details
Main Authors: Samy, Eileen T., Parker, Lucy A., Sharp, Colin P., Tung, Kenneth S.K.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212949/
https://ncbi.nlm.nih.gov/pubmed/16172257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041033
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