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IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites
IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites. Memory CD8(+) T cells lacking the IL-4R are unable to establish a stable population residing in nonlymphoid organs, al...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212849/ https://ncbi.nlm.nih.gov/pubmed/16087712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042463 |
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