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IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites

IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites. Memory CD8(+) T cells lacking the IL-4R are unable to establish a stable population residing in nonlymphoid organs, al...

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Autors principals: Morrot, Alexandre, Hafalla, Julius C.R., Cockburn, Ian A., Carvalho, Luzia H., Zavala, Fidel
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212849/
https://ncbi.nlm.nih.gov/pubmed/16087712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042463
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